PCI Biotech: Extension of preclinical research collaboration agreement with a top-10 large pharma company
NAc
technology has the potential to enhance the therapeutic effect of the partner's nucleic acid therapeutic compounds.
in vitro
studies, while this extension is supported by an expansion of the preclinical research collaboration agreement to cover evaluation of technological compatibility and synergy based on
in vivo
studies. The companies will evaluate the data generated in this research collaboration and explore the potential for a further partnership based on this outcome.
Per Walday, CEO
About PCI Biotech
PCI Biotech is a biopharmaceutical company focusing on development and commercialisation of novel therapies for the treatment of cancer through its innovative photochemical internalisation (PCI) technology platform. PCI is applied to three distinct anticancer paradigms:
fima
Chem
(enhancement of chemotherapeutics for localised treatment of cancer),
fima
Vacc
(T-cell induction technology for therapeutic vaccination), and
fima
NAc
(nucleic acid therapeutics delivery).
Photochemical internalisation induces triggered endosomal release that is used to unlock the true potential of a wide array of therapeutic modalities. The company's lead
fima
Chem
programme consists of a clinical Phase I/II clinical study in bile duct cancer, an orphan indication with a high unmet need and without approved products.
fima
Vacc
applies a unique mode of action to enhance the essential cytotoxic effect of therapeutic cancer vaccines, which works in synergy with several other state-of-the-art vaccination technologies.
fima
NAc
utilises the endosomal release to provide intracellular delivery of nucleic acids, such as mRNA and RNAi therapeutics, thereby addressing one of the major bottlenecks facing this emerging and promising field.
Forward-looking statements
This announcement may contain forward-looking statements, which as such are not historical facts, but are based upon various assumptions, many of which are based, in turn, upon further assumptions. These assumptions are inherently subject to significant known and unknown risks, uncertainties and other important factors. Such risks, uncertainties, contingencies and other important factors could cause actual events to differ materially from the expectations expressed or implied in this announcement by such forward-looking statements. PCI Biotech disclaims any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.
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Source: PCI Biotech Holding via GlobeNewswire